- Salvage Yards, Junk Yards & Wrecker Service, Trussville
- Salvation Army, Trussville
- Sand Gravel & Aggregate, Trussville
- Sandblasting, Trussville - General Contractors
- Sandwich Shop Restaurants, Trussville
- Satellite Descrambling & Programming Service, Trussville
- Satellite Dish Antennas & Equipment Dealers, Trussville
- Satellite TV Service, Trussville
- Savings Banks, Trussville
- Sawmill, Paper & Woodworking Supplies, Machinery & Equipment, Trussville
- Scales Retail, Trussville
- Screen Printing Supplies & Equipment, Trussville
- Seafood Restaurants, Trussville
- Secondary Schools, Trussville
- Security Alarm Systems - Home & Business, Trussville
- Security Brokers & Dealers, Trussville
- Security Control Systems & Monitoring, Trussville - Polygraph, Lie Detector, CCTV, Fire Sensor Equipment, Etc
- Security Investigative Services, Trussville
- Security Services, Trussville
- Senior Citizens Information & Services, Trussville
- Senior Citizens Service & Health Organizations, Trussville
- Service & Gas Station Equipment & Services, Trussville
- Service Establishment Supplies & Equipment, Trussville
- Sewer & Drain Cleaning & Repair, Trussville - Drain Cleaner & Installation Services
- Sewer Companies, Trussville
- Sewing & Yarn Stores & Supplies, Trussville
- Sewing Machine Repair & Service, Trussville
- Sheet Metal, Trussville
- Shoe Store - More, Trussville
- Shopping & Shopping Services, Trussville
- Shutters - Interior & Exterior, Trussville - Wood, Vinyl, Window, Plantation Shutters, etc
- Siding Contractors, Trussville - Vinyl Siding, Wood, Metal & Aluminum Siding Contractors - Installation & Repair
- Signs, Trussville
- Skating Rink & Hockey Operation Services, Trussville
- Small Appliances, Trussville
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- Smoked Meat Restaurants, Trussville
- Smoking Cessation Treatment Centers & Information Services, Trussville
- Snacks & Desserts, Trussville
- Soaps & Cosmetics, Trussville
- Soccer Clubs, Trussville
- Social Services & Welfare, Trussville
- Societies & Foundation Associations, Trussville
- Southern Style Restaurants, Trussville
- Special Events & Party Supply Rental, Trussville
- Special Interest Schools Or Instruction, Trussville
- Specialty Animal Services, Trussville
- Specialty Communication Companies & Services, Trussville
- Specialty Stores, Trussville
- Sporting Goods Stores, Trussville
- Sports Medicine, Trussville - Doctors, Physicians & Surgeons
- Sportswear Clothing Stores, Trussville - Sports Clothes
- Sprinkler Alarm Systems, Trussville - Fire Sprinkler Systems
- Staffing & Support Services, Trussville
- Steak House Restaurants, Trussville
- Steel & Metal Goods, Trussville - Steel Distributors
- Steel Detailers, Trussville
- Steel Manufacturers, Trussville
- Steel Work Contractors, Trussville
- Stereo, Audio & Video Equipment Dealers & Stores, Trussville
- Stock & Bond Brokers & Dealers, Trussville
- Stocks & Bond Brokers, Trussville
- Store Fixtures & Display Equipment, Trussville
- Structural Engineer, Trussville
- Substance Abuse Outpatient Clinics, Trussville
- Surveyor Services, Trussville - Surveying Service
- Swimming Pool, Sauna & Spa Contractors, Trussville
- Swimming Pools Contractors, Trussville - Install Inground - Above Ground Pools
- Swimming Pools Repair, Service, Supplies, Sale & Installation, Trussville
- Swimming Pools Supplies, Equipment & Accessories, Trussville
- Swimwear & Accessories Shops, Trussville - Water Sports Equipment
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