- Machine Shop & Tool Repair Service, Roanoke
- Machinery, Supplies & Equipment - Construction & Contractor Related, Roanoke
- Mail Delivery Service, Roanoke
- Mailing, Delivery & Courier Service, Roanoke
- Major Appliances, Roanoke - Household & Kitchen
- Manicurists & Pedicurists, Roanoke
- Manufacturing, Roanoke
- Manufacturing Products, Roanoke
- Masonry Materials & Supplies, Roanoke
- Meat Packers, Roanoke
- Medical Groups & Clinics, Roanoke - Medical & Health Centers
- Medical Supplies & Equipment, Roanoke
- Membership Sports & Recreation Clubs, Roanoke
- Mental Health Clinics, Roanoke - Treatment Centers
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- Mental Health Specialists, Roanoke - Psychologist, Psychiatrist, Psychotherapist, etc
- Methodist Church, Roanoke
- Mexican Restaurants, Roanoke
- Mini & Self Storage, Roanoke
- Miscellaneous Government, Roanoke
- Miscellaneous Professional, Roanoke
- Mobile Home Parks & Communities , Roanoke
- Modular & Mobile Homes For Sale, Roanoke - Manufactured Homes Sale & Service
- Mortgage Bankers & Correspondents, Roanoke
- Mortgages & Loans, Roanoke
- Motor Vehicle, Roanoke
- Motor Vehicle Rental & Leasing, Roanoke
- Moving Truck Rental , Roanoke
- Muffler Shop & Exhaust Systems, Roanoke
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